Alcohol can increase your risk of lactic acidosis from metformin. Alcohol may also raise or lower your blood sugar levels. Kidney problems warning If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. Liver problems warning Liver disease is a risk factor for lactic acidosis. Allergy warning This drug can cause a severe allergic reaction.
Taking it again could be fatal cause death. Warnings for people with certain health conditions For people with kidney problems: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis.
For people with liver problems: Liver disease is a risk factor for lactic acidosis. For people who plan to have an imaging procedure: This can affect how your kidneys work and put you at risk of lactic acidosis. For people with illnesses or plans to have surgery: Tell your doctor if you have a fever or infection, are injured, or plan to have surgery or another medical procedure.
They may need to change your dosage of this drug. For people with diabetic ketoacidosis: For people with heart problems: If you have a condition in which oxygen to your heart is decreased, such as recent heart attack or heart failure, your risk of lactic acidosis is higher. Warnings for certain groups For pregnant women: Research in animals has not shown negative effects to the fetus when the mother takes the drug.
This medicine is available only with your doctor's prescription. Your dose may need to be changed several times to find what works best for you. It is best to take this medicine with food or milk. Swallow the extended-release tablet whole. Do not crush, break, or chew it. Tell your doctor if you have trouble swallowing the tablets whole.
Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Read and follow the patient instructions that come with this medicine. Glucophage should be taken with meals. Your doctor may have you take other medicines along with Glucophage to control blood sugar.
These medicines may include insulin shots. Taking Glucophage with insulin may help to better control blood sugar while reducing the insulin dose. Continue your exercise and diet program and test blood sugar regularly while taking Glucophage.
For more specific information and recommendations, consult with your doctor. Does metformin affect the liver? If your liver panels are high, should you stop taking it? Since impaired hepatic function has been associated with some cases of lactic acidosis, metformin should generally be avoided in patients with clinical or laboratory evidence of liver disease.
This information is found in the package insert. You should discuss this with your health care provider and see what is causing the high liver panels and if you should continue with metformin. Do not stop taking any medication without first talking to your health care provider.
My doctor prescribed metformin for me because I am prediabetic. I took it for a week and a half. I started having stomach aches and felt sick. What should I do? I stopped taking it and feel better. Is there something else I can take? This is a possible side effect of the medication.
You should have informed your health care provider that you have stopped this medication and see what course of therapy your provider may want to do. You can follow a good diet and exercise to help delay the possible onset of diabetes. I have included some sites for your information. Be sure to talk to you heath care provider about your concerns. Does drinking alcohol affect how metformin works?
According to the prescribing information for metformin, one of the rare but serious side effects is a metabolic complication known as lactic acidosis. Alcohol lowers blood glucose sugar levels and can potentially increase the risk for lactic acidosis, so it is important to avoid drinking alcohol while being treated with metformin.
Lactic acidosis is uncommon but it is a medical emergency and must be treated in a hospital. Symptoms of lactic acidosis include weakness, increasing somnolence sleepiness , decreased heart rate, decreased body temperature, muscle pain, difficulty breathing, stomach pain, lightheadedness and fainting. You may want to contact your health care provider for more information regarding metformin and alcohol.
For additional information regarding metformin you may want to visit our website. What should your sugar count be? I am 57 years old, take metformin twice daily, and am tired all the time.
There are two different ways to measure blood sugar: A1C is a measure of blood glucose over the last 3 months. SMBG measures the level of sugar in the blood at the time the test is performed. Patients should work with their physician or healthcare provider to determine the most appropriate blood sugar goal. But again, the blood sugar goal from SMBG may vary depending on patient-specific factors. This information is solely informational.
It's important for patients to consult with their physician or healthcare provider about any specific question regarding their medical conditions or medications; particularly before taking any action. To visit Everyday Health's Diabetes Center, follow this link: Is it normal to have bowel issues while taking metformin for diabetes?
This information is solely educational. Does metformin cause weight gain? Weight gain is not listed as an adverse effect in the package insert for metformin. According to the U. There are various factors that can contribute to weight gain. It's important for patients to consult their physician or healthcare provider about any specific question regarding their medical conditions or medications; particularly before taking any action.
Derek Dore, PharmD Q: What are the long term effects of taking metformin mg twice daily? It is always a good idea to check with one's health care provider in matters like this. Please consult your health care provider for guidance in your specific case. What are the long term effects of taking four tablets of metformin a day. I worry about liver damage. Should I be worried about this or other organ damage?
The maximum recommended dose of metformin is mg per day. Liver damage caused by metformin is very rare. There have been only a few reported cases. There have been reports of peripheral neuropathy due to vitamin B12 deficiency, caused by metformin. You may want to speak to your healthcare provider about vitamin B12 supplementation. The main concern with metformin, over long term therapy, is accumulation of metformin leading to lactic acidosis too much lactic acid in the blood.
Lactic acidosis usually results in patients who have poor renal function, because metformin can't be excreted. Lactic acidosis can also be caused by poor liver function because the liver can't metabolize lactic acid. Liver and kidney failure can be the result of other conditions such as aging, cancer, excessive alcohol consumption and not necessarily caused by metformin. It is imperative that patients be monitored for decreasing kidney and liver function. It is also important to notify the physician if you notice symptoms of lactic acidosis.
Symptoms may include feeling weak, tired, unusual muscle pain, trouble breathing, unusual stomach discomfort, feeling cold, feeling dizzy and irregular heartbeat. What are the side effects of metformin?
I have dry skin on both legs and it is getting bigger and bigger. What is the cause of this? There have been no reports of severe dry skin as you described. Rash is very rare. There was 1 reported case of metformin associated with Lichen Planus. The main concern with metformin over long term therapy is accumulation of metformin leading to lactic acidosis too much lactic acid in the blood.
Lactic acidosis can also be caused by poor liver function, because the liver can't metabolize lactic acid. Liver and kidney failure may result from other conditions such as aging, cancer, excessive alcohol consumption and not necessarily caused by metformin. There have been concerns that metformin may cause a vitamin B12 deficiency potentially leading to peripheral neuropathy.
You may want to discuss vitamin B12 supplementation with your healthcare provider. What are the side effects of metformin and glyburide? The main concern with metformin over long-term therapy is accumulation of metformin leading to lactic acidosis too much lactic acid in the blood.
Lactic acidosis is very rare but can be fatal. Lactic acidosis usually results in patients who have poor renal function because metformin can't be excreted. Lactic acidosis can also be caused by poor liver function because the liver can't excrete lactic acid.
Liver and kidney failure can result from other conditions such as aging, cancer and excessive alcohol consumption. It is therefore imperative that patients be monitored for decreasing kidney and liver function. According to the research on glyburide, side effects include, hypoglycemia, liver function abnormalities, gastrointestinal disturbances such as nausea and heartburn, rash, photosensitivity, blood cell disorders such as leukopenia and anemia and low sodium in the blood.
I take mg of metformin twice a day. How many hours apart do those doses need to be? I'm considering taking them after lunch Generally, metformin is taken with meals, unless your healthcare provider instructs otherwise. When it is taken twice a day, it is usually taken with breakfast and dinner. Your healthcare provider is best able to guide your treatment choices based on your specific circumstances.
Consult your healthcare provider for more specific recommendations. What is the difference between metformin ER and metformin? I take metformin ER and I am passing the whole capsule the next day. My doctor kind of dismisses this but when I was taking the regular metformin my diabetes was under better control.
The difference between metformin and metformin ER is the formulation of the medication. Metformin ER is an extended-release form of metformin and is formulated to release slowly in the body. It is important not to crush, chew or break metformin ER tablets and swallow the tablet whole.
Breaking metformin ER tablets will cause too much medication to be released into the body at one time. The matter that you are passing the next day is the inactive ingredients of the tablet that may be eliminated in the feces and look like the original tablet. If you are concerned that your diabetes is not being optimally controlled, you may want to contact your health care provider to determine the cause and the best treatment options to meet your needs.
For additional information regarding metformin or managing diabetes, you may want to visit our website or subscribe to our newsletter. Would metformin ER make my mouth feel very dry and cause a bad taste? Although this is not a severe side effect, if you are experiencing a metallic taste you may want to discuss it with your health care provider.
For more information regarding metformin: Is metformin mg twice a day safe taken with glipizide 5 mg twice a day? Metformin and glipizide are often given in combination for the treatment of diabetes.
Metaglip is a combination product that contains both metformin and glipizide. Common side effects of the combination include headache, dizziness, nausea, and vomiting. Consult your healthcare provider for more specific information or if you have concerns about combining these two medications. According to the literature, the most common side effects of Glucophage metformin involve the gastrointestinal system.
Many of these side effects are temporary and can be minimized by taking metformin Glucophage with food. Please see the following Everyday Health link for more information on metformin. Laura Cable, PharmD Q: Why is metformin not helping to lower my blood sugar in spite of the fact that I eat properly?
Glucophage metformin is indicated as an adjunct to diet and exercise to improve blood sugar control in adults and children with type 2 diabetes mellitus. Metformin decreases the liver's production of glucose, decreases the absorption of glucose from the intestine, and improves insulin sensitivity. Metformin does not cause the pancreas to make insulin and therefore does not produce low levels of blood sugar or hypoglycemia.
In some patients, additional insulin production may be needed and metformin may need to be used in combination with another oral diabetes medicine. Does metformin decrease users food intake or make them feel full and bloated after eating? My husband has type 2 diabetes mellitus and, lately, he doesn't really want to eat. He says he feels better if he doesn't eat. Is metformin causing this? He is also on lisinopril and Lipitor. Although the literature does not state that metformin effects appetite, many patients have stated that metformin decreases their appetite.
Your husband may be experiencing the same thing as numerous other metformin users. Feeling bloated and gassy is a common and well-known side effect of the medication. Often, people report that this effect goes away after they have been taking metformin for a couple of weeks.
If your husband recently started taking metformin, then he will hopefully see some of these symptoms resolve within a few weeks. If he has been on this medication for a while, maybe he should talk with his doctor about the unpleasant side effects that he has been experiencing. As for the lisinopril and Lipitor, they are probably not causing any of these effects. What are the long-term side effects of taking metformin tablets for diabetes?
Metformin, when used over long periods of time, may cause a deficiency in vitamin B Normally, the vitamin B levels should be monitored every two to three years. If you do have a deficiency, a vitamin B supplement can be taken. The other side effects of metformin are normally experienced sooner. I'm taking metformin, but I've heard that it's very hard on your kidneys and liver. Patients with hepatic liver impairment should avoid metformin Glucophage.
This is because patients with liver disease have a risk factor of developing lactic acidosis while taking metformin. For patients with renal kidney impairment, the manufacturer recommends that they not take metformin in certain circumstances of renal dysfunction. The circumstances can be highly technical, so you should consult with your health care provider to determine if you fall into any of these categories.
LexiComp, the drug manufacturer, also recommends that patients taking metformin perform yearly renal function tests. Jennyfer Marisco, RPh Q: I'm a diabetic and take metformin and glipizide daily. Can either of them make me bloated? Metformin has the reputation of causing a bloated feeling in some patients. Discuss with your doctor whether you should try a fiber supplement to see if it helps with the bloating.
Matt Curley, PharmD Q: I have diabetes and take metformin. What does it do for me? Metformin is used to control blood sugar levels in type 2 diabetes. Some of metformin's benefits include a reduction in hemoglobin A1C levels an indicator of good glucose control in a diabetic patient , weight loss due to decreased appetite, and decreased morbidity hospitalizations and complications and death from diabetes due to improved glucose control.
Some studies also report that metformin has cardiovascular benefits, such as reduced heart attacks and strokes. When does metformin lose its effectiveness, and what is the next step in medication once this hapens?
Although there is some evidence that a tolerance can build up with any medication, metformin brand name Glucophage is well tolerated for long periods of time. Some patients do require further glucose control as their disease progresses.
In this case, metformin is effective in tandem with other medications of other classes for treating diabetes type 2. You should discuss with your doctor whether or not your metformin is still sufficient. If I need to fast for blood work, should I skip taking my metformin in the morning? I take it twice a day. Metformin should be taken with a meal. Though it doesn't usually cause hypoglycemia low blood sugar , it may if you aren't taking in enough calories with it.
You should check with your doctor about skipping metformin before a blood test. Kristen Dore, PharmD Q: What medicine, over the counter or prescribed, could I take for the nausea, gagging, and vomiting that metformin causes? I'm 56 years old and take it twice a day.
Nausea and upset stomach are side effects of metformin that generally go away after people have been on the medication for some time. These side effects can be reduced by taking metformin with food. Consult with your health care provider if these symptoms aren't going away, appear later in during your therapy, or disrupt your daily life. You may need to lower your dose, stop the medication for a short period of time, or switch to something else.
According to recent medical literature, patients who switched from metformin to extended-release metformin had fewer stomach side effects. It's important to consult with your health care provider before making any changes to your medication. I take metformin twice a day. How much food to I need to eat with this medicine? Metformin should be taken with a full meal, if possible.
You should take the medication at about the same time each day, with breakfast and supper. Gerald Levy, RPh Q: Why is it suggested to take metformin with a meal?
Does it help keep the sugar down for that meal, slow absorption, prevent sugar levels from getting to low, or to prevent an upset stomach? The reason I ask is because I seem to wait until an hour or two after dinner to take metformin. If there is a good reason it will remind me to take it with the meal. Does it help keep the sugar level lower 2 hours after eating?
Glucophage metformin is used to treat type II diabetes. Glucophage helps control blood sugar in a number of ways. These include helping your body respond better to the insulin that it makes naturally, decreasing the amount of sugar the liver makes, and decreasing the amount of sugar the intestines absorb.
Glucophage should be taken with meals to minimize gastrointestinal symptoms. Glucophage, as well as with other medications, should be taken exactly as prescribed by your doctor. Do not change the dose or stop taking the medicine without consulting with your doctor. For more specific information, consult with your doctor or pharmacist for guidance based on your specific condition and current medications. Why does metformin make my stomach cramp? Metformin Glucophage is a medication used for the treatment of diabetes or high blood sugar.
It works by decreasing the production of glucose by the liver. The main side effects of metformin Glucophage are gastrointestinal in nature and include diarrhea, nausea, vomiting and flatulence. These side effects can be diminished by taking metformin Glucophage with food. These side effects also tend to improve over time, so if it is a new medication, the side effects will likely get better. Your healthcare provider will be able to provide you with more information.
For more information on metformin: I take metformin for type 2 diabetes. I find I have terrible gas and indigestion since I began the medication over a year ago. Common side effects of metformin include nausea, vomiting, gas, and stomach pain.
Your healthcare provider is best able to evaluate any side effects you may be experiencing. Consult your healthcare provider for bothersome side effects that do not go away.
Does metformin cause hair thinning? I have been taking it for four years and my hair has gotten much thinner. There are no documented reports of hair loss with the use of metformin. Here is some more information about metformin: Can you take metformin just when your blood sugar is high? I control my diabetes with diet and exercise. When I cheat by having a piece of cake, I try to work it off exercising. According to drug information sources, metformin is dosed every day, not as needed. When your physician decides to start you on a medication for diabetes, there are several factors that go into this.
The first is what your daily blood sugar levels are. Physicians often also look at your hemoglobin A1C levels. The hemoglobin A1C levels reflect the average of your sugar levels over a prolonged time period. Another thing that must be taken into consideration is what other health conditions you have. If you have other medical conditions, your doctor may treat your blood sugar levels more aggressively.
Never change your dose of your medications without talking to your healthcare provider first. Occasionally, patients are able to decrease their diabetes medications or stop their medications after improving their blood sugar levels through diet and losing excess weight.
This should only be done under the supervision of your physician. As always, talk with your healthcare provider regarding questions you have about your medications and medical conditions. For additional information regarding diabetes: Does metformin damage your kidneys?
And is it good for people with diabetes? Glucophage metformin is used to treat type 2 diabetes. Common side effects of Glucophage include diarrhea, nausea and upset stomach.
I have been taking metformin mg twice a day for the past 2 years. I understand that long-term use of this drug causes kidney problem. Can you please explain? Upon looking at research articles and drug references, there is mention of metformin Glucophage causing lactic acidosis. Because metformin Glucophage is excreted by the kidneys, patients whose renal function kidney function is below the normal range for their age group, should not take metformin Glucophage.
The medication also should not be used in patients who are dehydrated or have pre-renal azotemia. Please keep in mind that diabetes itself can cause damage the kidneys. As always, consult your health care provider regarding your specific concerns about your medications. Below are links that provide additional information about diabetes and metformin: My doctor upped my dose of metformin from mg twice daily to mg twice daily. Now I have diarrhea and nausea, also leg cramps.
Glucophage generic name is metformin works by affecting the production of glucose that comes from digestion. Side effects of metformin can include diarrhea, headache, nausea, and stomach gas. These side effects usually occur when the medication is first started or whenever a dose is increased. If a side effect becomes too bothersome, contact the physician. Never stop a medication without a physician's approval. Since I have started taking two mg metformin tablets, I am having breathing problems.
Should I stop taking it? Studies have shown that some people have developed a life-threatening condition called lactic acidosis while taking metformin. You may be more likely to develop lactic acidosis if you have congestive heart failure. Older adults may also have a higher risk of developing lactic acidosis.
Talk with your doctor about your individual risk. The following link will provide additional information about treating diabetes.
I take mg metformin, twice a day,once in the morning and again before retiring. My blood sugar readings have been high, in the 20s and down to only about 15, for quite awhile. What do I do to get this under control? I must add that I take lots of other drugs for a heart condition. Metformin Glucophage is a common oral medication used to treat type 2 diabetes.
Metformin Glucophage is usually started at a lower dose of mg twice a day and can be increased weekly by the prescribing provider. Talk to your doctor about increasing your Metformin glucophage dose if your blood sugars are elevated. Insulin doses can also be slowly increased as needed by your doctor until blood sugars are under control.
Blood sugars in the 20's or lower are very low and a patient would probably be unconscious with readings this low. Talk to your doctor about what your goal blood sugars are.
There are many things that can affect blood sugar levels in patients with diabetes. One variable is the time of day that you test, especially in relation to when you last ate. In general, it is best to test before eating or 2 hours after eating rather than immediately following a meal. The amount and type of food you eat can also have an effect.
Check food labels for the amount of carbohydrates in the foods you are eating. In genera,l the more carbohydrates a food has the higher it will raise your blood sugar. It can help to have some protein with your meals and snacks to keep your blood sugar from going as high. For example, for a snack you could have five whole grain crackers with 1 oz of cheese or 1 tablespoon of peanut butter instead of having 10 crackers alone. Exercise and illness are two other contributors to blood sugar levels.
Exercise can help lower your blood sugar lower while many illnesses can raise your blood sugar. If you miss a dose of your diabetes medication or take more or less than prescribed, you will also notice a change in your blood sugar.
It is best to keep a log of your blood sugars and note the date and time as well as when and what you last ate and if you exercised before the reading. Take this log with you to your doctor's appointments, it will help your doctor determine if any changes need to be made with your medications. Please see the following Everyday Health link for more information on diabetes and how you can control blood sugar levels.
My nails, which have always been strong and healthy, are splitting, chipping and in general a mess! Can I take something to combat this?
A friend suggested biotin mg. Common side effects of Glucophage include diarrhea, nausea, and upset stomach. Other side effects reported with Glucophage use include nail disorder.
These are not all the side effects of Glucophage. For a complete list, ask your doctor or pharmacist. If you have questions or concerns, talk with your doctor or other health care provider.
Does metformin cause loose stool and undigested stool? If so what can we do? The most common side effects of metformin Brands: Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet are stomach-related problems such as diarrhea, mild nausea, vomiting, gas, and stomach pain. These side effects usually only occur during the first few weeks of taking Metformin and typically improve over time.
Work with your doctor to determine the dosage and timing of Metformin that is right for you in order to minimize these side effects. These side effects are shown to be much reduced when Metformin is started at the lowest dose, usually mg a day, and then slowly increased to the recommended dosage. An extended release version of Metformin, Glucophage XR, may also help reduce gastrointestinal problems through a slow release process.
Also, diarrhea, nausea and upset stomach are greatly reduced when Metformin is taken with a meal. Lastly, it is important to reduce the amount of fats and sugars ingested while taking Metformin. In fact, consuming a diet high in fat or carbohydrates while taking Metformin can make stomach upset or diarrhea worse.
People who take Metformin with a low-carbohydrate diet find that stomach upset is minimal. If stomach upset and diarrhea persist, such symptoms can be treated with over the counter anti-diarrhea medications such as Imodium and Gas-X. If these side effects last longer than a few weeks and do not resolve with a modified diet, consult with your doctor.
I'm currently taking metformin. Why does it have a fishy smell? Can I switch to something that doesn't smell? It has been reported in the news that some formulations of metformin have what is described as a "fishy odor" or a "locker room odor. The smell is primarily associated with the immediate-release form. Some patients have found that holding their nose while taking the drug may help. However, others are so bothered by the smell that they cannot take the medication.
If you find that the smell is bothersome to you, consult your healthcare provider. Other forms of metformin are available that have little or no smell at all, including the extended-release formulation. Your health care provider can help determine whether switching products is appropriate for you. I feel very tired. I take metformin, mg two tablets a day. I also take vitamins and iron. My TSH is a borderline of 4. What should I do feel energetic?
According to the package insert, metformin can cause a feeling of weakness. A feeling of tiredness or fatigue has many potential causes, including hypothyroidism, lack of exercise, too much stress, and trouble sleeping or poor quality of sleep.
If it is the regular-release metformin, I'm thinking about asking my doctor to switch me to an appropriate dose of Januvia and the timed-release metformin Glucophage XR extended-release tablets.
Are there any problems or cautions in switching? There should not be any issue in converting to Januvia sitagliptin and Glucophage XR metformin extended release if dosed appropriately according to your physician. Any time that medications are changed from standard release to extended release, the dosing needs to be adjusted to accommodate the longer-acting nature of the extended release. I have diabetes and take mg of metformin twice a day, but my sugar levels are creeping upward.
I live in Mexico during the winter, and there is no doctor here that specializes in diabetes. If your blood sugar levels continue to increase, you should consult a physician to see if a dose adjustment or other form of metformin Glucophage, Glumetza might be warranted.
Hopefully you could at least have a phone discussion with the prescribing physician if there is no local physician. Always remember that diet, proper nutrition, and exercise are also important in controlling diabetes. I had to discontinue my metformin because of side effects and am now just taking Januvia. If my AIC levels come back within range, do I need to go back to taking metformin?
I understand that it is the "first" line of defense. My side effects were from metformin HCL. My doctor had accidentally written my RX with that instead of metformin XR. I did not seem to have bad side effects with the metformin XR.
I will be back to see her within 3 months. Metformin is the first line treatment for your condition, but in cases where metformin is not tolerated, Januvia is a good second choice. In the prescribing information for Januvia, a study done with participants on weeks of initial therapy, Januvia lowered A1C levels, which were sustained over 2 years Q: How can I stop taking metformin?
Metformin is a very effective medication. I am not allowed to discuss discontinuation of therapy without your prescriber specifically instructing you to stop your medication. However, I cannot overestimate the importance of this medication.
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